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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55fdd5758658f48761813006f912d4f7adb959ab99ed0f5dd9fcf7058d06d621' 
  AND token = '7lnVW6uh5qHcZ6PAHOt4xEuy3G0qOGBOi8K9Flj7a24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}