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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9168360164dd758216f2564cc812640a2d32f1c918e1b6f92625f863f473e6dd' 
  AND token = 'aPaRkZsXGSRDzoNBT+rEZXUTuNB8PqapjoM1cyhukm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}