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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d00879c374460230f57aedd27471806f2c67a121735fc5d69b0fbd29dcefd2' 
  AND token = 't9udT3C9TiczZTXmtX6pzLhMvdtR8AjIt+h6iQ1+pwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}