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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6fba95095aa41ca494c3b4f0a7824be89bfe4912edeecf3ebe599358f1cc611' 
  AND token = 'GTbz5+qMFh37O21AdqaYiNFwbUGc3I13WNddzgSLf5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}