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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c6375986eaf7c7547e9d07bb78c9d01d7ee9d54af997fb3856fdf175336562' 
  AND token = 'XSY89keNS6GZ3uxlfHZaNP8XwA/aixp9Ir1HogYYTsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}