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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5da493f8b66e0255d619f1ea932237d8222ec3c485482ffac6d5edc683a8886d' 
  AND token = 'w3SZbTC4QGZ2x7gi3dXdGkbrKVHhgmB9+9ilL4vTZ3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}