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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e17789b7f0af50bb440d9e1d84eeb06af7e13b5d045a2fa50d65e4fe2edf42' 
  AND token = 'FpXURTcrvt+cspArALXKofWCR3kvGgqH1446fFGpSuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}