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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e68b37cb4da6663b25c13d7a235d02327459695e4286557d4a2930375d026e' 
  AND token = 'CRrPXqmPDbfHF5iRme8RMeahot3GUXUPH1VrIZO9I6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}