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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48de11f56ef7bec78a8a02b07430dd5d2af5675bcef1348d29702b1c4a780310' 
  AND token = '5dySms2G8d2b+rolApA27cbEnUUzzOQbV1OKpfH+3cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}