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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cca5e04e56cd8ab1df23c436fab7b9c8a7829990c1b78f8bbfaf742a1e0aff4b' 
  AND token = 'XjMfoHTplBotoZ5687Vy4TBLbHYA6h/u4z1F/awVD0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}