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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89eca2fcb1c9d83aac3e0517f6c3044486231818e367a7893b1991abdd597d8c' 
  AND token = '2ZGS3zJGh0w3+EduQ2ImawotnLKA8BeB+KI1Sxl3o0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}