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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c06a2b48e7875bf2f0caeedab7de04e73e5df6d20898adfbae9552ad9e679721' 
  AND token = 'Jx/XhUep99mzGDc20BKwI9BgYe2Xctjw7ouyS/HEWoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}