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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ed27b8756ba8b28689a4809a09706ade7256229d9389d89eeb86704351d2dc' 
  AND token = 'GEqcyhMsOcXRpYQMlA1XVsF9RUGbkY5TF6vGFAyE4eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}