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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57aaa5ff0f720531aa8f4a34049a50e05af22c5a2374f91db1b2c7dbf0ace8d9' 
  AND token = 'KoW6Nc5d3FNlDrAkXu5uv4zMGehfmCKyJg6vrm8spLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}