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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab3352ea605e67548973c58cbbd010d244937df55b6c42fec6b072ee8f1421ea' 
  AND token = 'TsFMEvZbrAdqEUL5SrMpDTJch0nN8zTUBX4T5p5GYUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}