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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ebd6638a10b9fbbdf1b02992eb8501238096d51f236af6bedb9dbc94668bd65' 
  AND token = '8gogWMlv7Mc163aRY+AhK9gUG9LgOiWFYKCUXO7BFM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}