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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a593111f89dd6b1c2eaff27c5bebc8724739e57c700ffc32daf686b3b40249a4' 
  AND token = 'sY9HX1N+uz3ktBnted2tD+6rGB+GVXsiogOSt62Rb8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}