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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ceb8d735a340b597fd3b8d27b3905e65187c164be7cf6ebd6a6e915433e4cec' 
  AND token = 'npPgQPVwQZT/PUdpHyjQTxF3zH7x4v3ESQO9FsJ5QRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}