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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a68cc6fe7f5823b41fb680805f81668cc4300d1bc621290dfd2abb142196119' 
  AND token = 'CdtN5EnpI0sIuIGE9VRSwA0G9x1QaZUb5T6ymvCmvjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}