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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8828457a13cd5c147b41260538da3a140160932d637df523910200daee6cdbd4' 
  AND token = 'okUiPBNHz+IXJb06CG6a0pDWxCiPjO7V5v1AOWkW9ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}