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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1ae8e38c6c5382cc0d8d25f5ed864ef021addd02e536d38dc1ab22d39a563a' 
  AND token = 'CGgCvNGYaEPgfK+2/eyPQpxtz6Xs0gCHlYSyNCRiwqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}