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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1a602c8970ef43486941a495d79d7bc11b37c78b667381b63e5e0cba5bdba6' 
  AND token = 'fI2LN6kbkEjIVBg7mt/Pimn4tsabVofFrWoit4h9Q+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}