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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ad0e2e7c8c1134b59712f8a21cf839a7da08984cd6cfa570879938eaf35ccb' 
  AND token = 'gTbe307fqEUslztq+X+gvi++kw9kJ8WqdqJ93CBYjqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}