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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb7e26c516ee7eeee206d201a4abc9133266eba52ba4be2cd8bd990fbddb901' 
  AND token = 'p9+PNs/zLVnXwgbl8PbjLZHOAvPaGMCawa6XOnFOiBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}