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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f14b192448bc038580b7a0c01652408fd652691fdf792d9343e0d1c680d6ea' 
  AND token = 'ueWd1/1EFxQomtAIYpfnUYD39Wixa8EvIUl1ZScEmnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}