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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad3288f629abeadf75b7cd14b0fa71d4e806f93f8759213f2f1035aa709d0e36' 
  AND token = 'AxEqsd3Wpw1rI9D6FeIicHW1CxWdwpQ7knyEymAkX+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}