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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147a0610c3a30b880468eb8cb317e09bdd6c585d71e6d098324d942aee7e6733' 
  AND token = '0RAwcKzDHyrQmI7B0BaTjBADBGD8sDbT5+8K+iW1LWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}