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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb59bada0b5a58ee746d97363ec0d28721a16b4235e3237660acc6f9f985481d' 
  AND token = 'nCanVYUa8OBxM19yM/TEv19EzGbk+tCBHuYiGwMIbyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}