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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2681717ac16dfa859c65ed6af16e46f7a476bfa104d8c1bde2d335f4ef199c78' 
  AND token = 'GF4Dga4gJxPT75eWZxS2mE1WyH1iangC3JuSYyLPDIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}