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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3cbb2b859544ef6c1348a9a8e20bb0c9bde0c70be3c927202f08efe5f6c48f' 
  AND token = 'S0/rvaB8GKGFhPNT0sMeJl3uwWvnk/wKq6ctY0qEKx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}