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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f74845e65adf980b5914c5003ea1722995f8c772c1ddc2e5b0a16f921c216cff' 
  AND token = 'qZq44Wakw9O4YDZ1sG/HaSV7ALnpnrYi3vCNsGzCbpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}