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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724358eb2ea32fdb3ac046ec555c1214c8d68c2f7df2ae3b8d851f228c4fce0d' 
  AND token = 'YbSR/WKOduAL7PT+oGGhL2nSAElHp9PpYgh3JP6/qTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}