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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544d77a5dca154fbc467f36756375a14e8d4fd2713730fe5090b5f001b172604' 
  AND token = 'OoPsLm5MxgOtPtDQC7s+1eEj/3DNk4quTDKlhIqZX5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}