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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '284889dc8107c3bdf83cee528f59f65df7f3c5cb5a8ff36d8c9917ae91de10ac' 
  AND token = 'VGrWi8qnmZCCLNjssHbMW6tZm6ZBnu0VlO86bDVbK5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}