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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef979a79890d46a63317f13dd0fc6dee0eb45ccf6c602ed398b255cd0c7e291f' 
  AND token = 'aFVWjtB0Q/sFOh7KKRKxcC0TRZEPaN2ZU4WrTz4YUn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}