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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54196101df44803806ce9dd1d4f34a27fd2bf864dfd4bfe34f043b0c801bc945' 
  AND token = 'AJb4aQWjzxEUrxcLz35IRJeRF8oXzfKm5QHynLlOacU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}