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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd54c7da369cb0831ccd565c24ac05c8e4158fdc55b6c062103c97d9e83a4e83f' 
  AND token = 'JhNJyEkEkjADF9/sYkJc0uRjQI623zWSDSHFJ3hOtY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}