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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6284dcaa7986282c8de99c80f4249bb1f33fd7fb0e72cf34814e0a0458d42868' 
  AND token = 'S3eFI+u6HJlvjz4qvfjoWf+5PDNbSDBMls9JkqjCI2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}