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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123d50833f33968da36695e5a54e3aa1c38d19180ec4dc346f7aa4255824901d' 
  AND token = 'LVUrqI12ySrqRn6fNFofCFlQAFWGPB8bTBROKn8RvIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}