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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a248ec10f860a29cab77d26d46a27748b79ecc31c335a8cc5de8471a3e286881' 
  AND token = 'uC/PHmjwrig9vL2H9QPFrJVowHFEUosXbV7UiTWMZ58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}