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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224556d19fee4abb2859ac333cf0c1869261f0126c453a41500778665f0dbcae' 
  AND token = 'GLCAT6aCUGFWkW0Npauy5j8sfJEu2XEey9YkGE/zQno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}