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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b44e970645b117d5ae0fc68463d4b6e9367ba45c4feb1c37a85f4775721a7a8' 
  AND token = 'eLPW7ISD7bbBzzaKsd/YTUtBJZBypn4SNF8S515Trh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}