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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaaf0cf9893eff639cc1edf935866ce957f1c81054c1ef7c9699039150164c7a' 
  AND token = 'nSI3QWtwgsPCwQ15GWgR+eCb8kcBIUdw/IZ0rUpmCbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}