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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cfeb839fa5e57f2ca43eab4024d4180f26eddc447e5fcb7ead5fab0bb11f099' 
  AND token = 'aubS9Luhg0+YAyiRr19MQ0Fto16zfDHq2WcHuHZ5gKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}