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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a33a82b2976e9949d4659c8a2fd71fce99e92f076294e0de4872355a82482029' 
  AND token = 'sb5MsHuch3P0fIFRXShbD7kfsn+Y1yTDsv7eh5ZUCAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}