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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '510c3879083156236c46a1e56c57a33dd105b65aed4c8aedb1c9d19dc3e49e99' 
  AND token = 'Q/lMZPr2ACE7WPExc54ehZzrHVmpgBvXGwpt0j1Z4Os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}