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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40dc42b585dbdded3ba946652402918b60917681cd940d86aee0ee1c33feab07' 
  AND token = '7EqZwofaxrLp9Y5o+Tj1A/ByjERELJtjeZigNdPfHSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}