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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61cd47772165beb954759c5014e4afe88e3a23af6460f4c1a8a2cde5b08436eb' 
  AND token = 'OkrM0zcNaEiMeNfwVsnW4Zpn8bDAcuFQEgufFuKtlKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}