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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f89573b34b5966e2f441416c70a1103006fd1a63de6a3eb3cdf62680eb7589' 
  AND token = 'b7MxU9ZMS4OaMh7gvyDXWNCurk2E6ZdwMY6GJlKHOZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}