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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f55eadddea131303ed5f718c7ac65b21950c72c68b70021d248822513bf9d58b' 
  AND token = 'ETNuGU9ISzG/Ml6hkKD1/m4XsS5JmPiHPEnHI43fdjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}